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I am an analytical chemist and my research area is the sample preparation, mass spectrometry, material chemistry and clinical chemistry. During my first postdoctoral position at professor Janusz Pawliszyn’s research group, I worked on developing two microsorbent chemical devices, called thin film membrane device and needle trap device, using solid-phase microextraction techniques for capturing more than a hundred reported metabolic marker compounds associated with various diseases from the human breath tests. Later, these devices were coupled to portable GC-MS and this configuration enabled us to integrate sampling, sample preparation and finally analysis of breath biomarkers in a single platform. Our designed breath-based analytical devices were utilized for on-site point-of-care detection of lungs cancer marker compounds at the Toronto General Hospital, Canada (S. Zeinali, C. Ghosh and J. Pawliszyn, Analytica Chimica Acta, 1203:339671, 2022). To make our technique more versatile and sensitive, we incorporated polyvinylidene difluoride, a thermally stable polymeric material in our material-based coating recipe during the development of the mentioned devices. This revised configuration of the devices made us possible for both gas chromatography and liquid chromatography mass spectrometry applications through a single channel (USA Patent, 16/704426, C. Ghosh, V. Singh, J. Grandy and J. Pawliszyn). For further application in environmental field, we have utilized one of the devices to develop a purge-and-trap analytical technique for the on-site monitoring of the level of butylated hydroxy toluene (BHT) compound from the skin lubricants. To further validate this technique, we randomly checked the toxicity level (as per guidelines by the Cosmetics Ingredient Review Board) of the following compound from the random cosmetics samples from the Canadian market (C. Ghosh, V. Singh, J. Grandy and J. Pawliszyn, RSC Advances, 6671, 10, 2020).

After spending almost 2yrs at the University of Waterloo, I joined Dr. Koo’s research group in the Harvard Medical School & Mass General Brigham, USA. Here, I have worked on developing the passive and active sampling tools by utilizing polymeric sorbent materials to capture the microbial emitted volatile metabolites in breath for screening of the fungal and bacterial infection in the immunocompromised cancer patients. This study was based on the fact that certain microbial and host volatile metabolites are present in the breath of patients with pneumonia caused by bacterial and fungal pathogens, providing a diagnostic target for these pneumonia. 

Editorial Position

Dr. Chiranjit Ghosh

Topics Editor (2020-present)

Separations Journal, MDPI Publishing Group

Special Issue:


Feb, 2020-2022

Postdoctoral Research Fellow

Division of Infectious disease,

Department of Medicine

Harvard Medical School/BWH

Harvard University, Boston, USA

2018- Jan, 2020

Postdoctoral Research Fellow

Analytical Chemistry

Professor Janusz Pawliszyn's Laboratory

University of Waterloo, Canada


PhD Researcher (Chemistry)

Dept of Chemical, Biological & Macromolecular Sciences

Satyendra Nath Bose National Centre for Basic Sciences, Kolkata (A Autonomous DST Inst. under Govt. of India), University of Calcutta, India


Research Assistant (Chemistry)

Dept of Chemistry

Jadavpur University, India


Analytical Chemistry

Sample preparation, Solid Phase Microextraction (SPME), Needle Trap Technology

Cavity Enhanced adsorption spectroscopy

Stable Isotope analysis

Biomedical Science

Breath analysis, non-invasive diagnosis of diseases like diabetes, Helicobacter pylori

Gas Chromatography, Liquid Chromatography,

Mass Spectrometry

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